The Non-Aligned Movement (NAM), a 120 Member organisation, being the largest collective voice of the developing world, has voiced its concerns regarding the adverse impact of COVID-19 crisis. The article would study how the NAM has responded to the COVID-19 articulating the interests of the Global South. On May 4 2020, an online Summit level Meeting of the Non-Aligned Movement (NAM) Contact Group in response to COVID-19, under the theme of “United against COVID-19 pandemic” was held and the declaration adopted at end of the summit outlined the position of NAM calling for global solidarity to fight the pandemic. The article would also study the role played by NAM in multilateral bodies such as the United Nations General Assembly (UNGA) and the United Nations Human Rights Council (UNHRC). The Non-Aligned Movement has been at the forefront to point out in multilateral forums against disparity in the distribution of vaccines against COVID-19 between developing and developed countries. NAM has also supported the World Health Organisation’s (WHO) Declaration on Vaccine Equality. The article will thus study how the Non-Aligned Movement articulated the interests of the Global South in times of COVID-19 crisis